Pyro's Legacy infection was revealed in X-Men Annual (2nd series) #2. He died defending Senator Kelly in Cable (1st series) #87, as the virus finally took its toll.
Pyro was one of many mutants resurrected by Selene's control of the techno-organic virus in X-Force (3rd series) #21. Several mutants reportedly did not return to their graves after the Necrosha event ended, and the original Pyro made several appearances afterwards, presumably as a result of this. However, he also confirmed he was resurrected on Krakoa in Marauders #1.