Universe/Timeline:
Marvel Universe
Spider-Man's deadliest foes, joining forces to defeat their arch-nemesis. In some incarnations, the team actually operates as the Sinister Seven, Sinister Twelve, even Sinister Sixteen.
Other members have included Kraven, Electro, Mysterio, Hobgoblin II, Gog, Beetle, Shocker, Scorpia, Venom, Mysterio II, Kraven II, Hammerhead, Tombstone, Lizard, Hydro-Man, Boomerang, Beetle VI, Overdrive, Living Brain, Cyclone III, Shriek, Scorcher, Human Fly, Mirage, Clown II, Armadillo, Spot, Squid, Swarm, Killer Shrike, Melter III, Delilah, Iron Spider, Bombshell, Electro III, etc.