The primary heroes of the Ultimate Universe. The original roster included Ultimate versions of Nick Fury, Captain America, Thor, Iron Man, Hulk, Giant-Man, and Wasp, with Hawkeye, Quicksilver, Scarlet Witch, and Black Widow shortly following. Other members included Falcon, Ka-Zar, Shanna, Black Panther, Valkyrie, Power Princess, Captain Britain, Monica Chang / Black Widow II, Spider-Woman / Black Widow III, Invisible Woman, Thing, and Human Torch.

The All-New Ultimates formed in the aftermath of Cataclysm and the disbanding of the original team. They included Miles Morales, Kitty Pryde, Black Widow III, Bombshell, Cloak and Dagger.