In the Ultimate Universe, Andrea and Andreas von Strucker were the owners of Fenris International, a multi-billion dollar enterprise that secretly made use of mutants for various endeavors. The Struckers kept their private life private, not openly acknowledging they were mutants, and even leaving it ambiguous whether they were brother and sister, or husband and wife. Ew.
They first came to the attention of the X-Men when their agent Gambit kidnapped Rogue in order to make her an offer, although both ultimately refused to work for Fenris. Later on, they manipulated both sides of the human-mutant propaganda by secretly supporting Stryfe and his Mutant Liberation Front to stir up feelings of mutant persecution, while also funding Bolivar Trask and the return of the Sentinel program. Bishop's X-Men uncovered their schemes and the duo were killed by the time traveler.