BIOGRAPHY - Page 1
Regan Wyngarde is one of the three known children of the powerful illusionist Jason Wyngarde, aka Mastermind. Much like her half-sister Martinique Jason, Regan is even more powerful than her father, as she has mild telepathic abilities which allow her to insert hyper-realistic images into her victim’s mind. Whilst her early life is shrouded in mystery, it appears she was well aware of the existence of Martinique and the fact that her father was a super-villain. Regan didn’t come out of the shadows until after his death, when she took the name Lady Mastermind as a way to honor him.
Regan was hired by Sebastian Shaw, who was seeking revenge on his former assistant Sage for her betrayal of being an undercover agent for the X-Men. Sage was operating as a coordinator for Storm's team of X-Men when Lady Mastermind struck. 
While it would have been easy to place Sage in an illusion and simply kill her, that wasn’t Regan’s style. Instead, she decided to pull specific memories from Sage’s mind and force her to live them over and over again, slowly twisting them each time. Unfortunately for Regan, Sage had formidable mental abilities herself and managed to see through Lady Mastermind’s illusions to begin with and knocked her captor out. Sage was soon captured by Shaw, though, and Regan adjusted her technique and overpowered Sage until she was catatonic.
The ultimate goal of the plan was to destroy any good memory of Sage’s time with the X-Men and leave her with a complete devotion to Shaw. Unfortunately, Sage’s fellow X-Men complicated things when they became involved and Regan had to use her powers to deal with them too. When Rogue squared off against her, Regan entered the X-Man’s mind and found one of her deepest fears and exploited it. She made Rogue believe her team had been killed by a man named Vargas and so the super-strong woman went on the warpath. Regan then stuck close to Rogue, manipulating her into seeing Vargas every time one of her teammates showed up. Regan’s downfall came from one of the X-Men’s newest members, Lifeguard, who could manifest any power she needed to save someone’s life. Entering Sage’s mind, 
Lifeguard tried to free her from the illusion but became caught up in Lady Mastermind’s tricks herself. In a deadly showdown in Sage’s psyche, Lifeguard managed to turn Regan’s powers back on herself, causing a huge psychic backlash and putting the illusionist in a vegetative state. [X-Treme X-Men (1st series) #6-9]
Regan remained unresponsive for some time and her body was somehow obtained by a clinic that experimented on mutants. When most of the world’s mutants were depowered, Regan managed to retain her powers and the X-Men’s mutant detecting device Cerebro picked up her power signature. As there were so few mutants left, the X-Men investigated and they found her in a hospital alongside the Sentinel-cyborg Karima Shapandar. After a fight with the surprisingly well-armed soldiers who were guarding the women, the X-Men took the still-comatose Regan back to the Institute to recover. [X-Men (2nd series) #188]
Even though she remained unconscious, Regan’s powers still proved to be dangerous to those around her. When the Children of the Vault attacked the X-Men, one of their members, Serafina, found Regan and bio-cybernetically hijacked her body, using her powers to envelope Cannonball in an illusion. This intrusion was enough of a stimulus for Regan to regain consciousness and she awoke to find herself wearing a rather unfetching hospital gown in the X-Men’s medical bay. Beast explained to her how the X-Men found her and the only clue as to who initially captured her was the name “Pan.” Regan didn’t care, though. She set her sights on Serafina and joined Rogue’s ad-hoc team of X-Men in a bid to gain revenge.
When Rogue discovered that Pan and the Children of the Vault were linked, she took her team to storm their giant flying ship. Despite having just woken from a coma, Regan managed to aid the team immediately by creating a distraction to fool the Children. Once on the ship, the two groups got to fighting and Regan quickly showed that, while she was technically one of the X-Men, she didn’t hold to their no-kill policy. When she was seemingly cornered by some of the Children, she used her illusions to trick Fuego into killing Ajuda and his allies. The Children were eventually defeated and Rogue’s team of X-Men were allowed to keep operating, despite the presence of Lady Mastermind and some other villainous members, like Sabretooth and Mystique. [X-Men (2nd series) #189-193]
Regan quickly proved quite useful by using her powers to identify one of the men who used to work at the hospital in which she had been held captive. As they were interrogating him, though, Regan’s mean streak became apparent for all to see. When they tracked down more hospital workers, Regan couldn’t help but kick one square in the head for the fun of it. Rogue reprimanded her for her actions and reminded her that she was only on the team because she had a personal stake in the mission. The group soon discovered that the man behind everything, 
Pan, was a scientist named Richard Palance. Unfortunately, when they found his base, they fell into his trap and he kidnapped Rogue and knocked the rest of the team out. Lady Mastermind was none too pleased with the situation but she stuck with her team and together they used a teleport gate to follow Pan and Rogue. When they eventually discovered Pan’s real base, they were confused, as it wasn’t exactly in a private area.
However, Regan knew she was being tricked and used her powers to reverse the illusion around the area and show it for what it was. They entered the building, which turned out to be a very advanced laboratory, and Regan let loose on the soldiers guarding the place. Regan had been having headaches ever since she woke from her coma but something new happened when a bolt of energy erupted out of her head and knocked one of the guards out. Iceman was shocked by what had happened, but Regan dismissed it and continued her onslaught. 
When Pan arrived, though, he proved no match for Regan, so he turned her illusions around on her and knocked her out. Regan was taken by some of the doctors and was about to be vivisected but she was saved by Mystique. Meanwhile, Pan had been loading himself up with various mutant powers but he was eventually taken down by Rogue. However, before she could deal justice, she fell unconscious and so Lady Mastermind happily got payback and trapped Pan in a persistent illusion where he was lost in a giant maze. [X-Men (2nd series) #194-196]
As Rogue’s condition was getting worse, Cable took her to Providence, his island base, and Lady Mastermind tagged along for the ride. Cable made it perfectly clear, though, that he didn’t trust Regan one bit and warned her against acting out. Cable’s distrust was not without merit, as the moment he left Regan took the opportunity to use her powers to explore his base and locate the psychiatric unit. Her recent headaches and power fluctuations had alarmed her enough to seek help, as she could feel that there was something sinister lurking in her mind. The resident psychiatrist wasn’t keen on Regan’s impromptu visit but an illusion of a squad of armed guard convinced him to look at her case.
With the combination of her own powers and some hypnosis, Regan was able to walk through her own mind and she quickly discovered that she was correct in her instinct that she wasn’t alone. However, when she tried to interact with the parasite in her mind, it took control of her and starting lashing out with her powers. The parasite was an entity called a Mummudrai and it had come with a warning for Earth. The Hecatomb, an ancient Shi’ar psychic weapon that fed on people’s minds, was descending on the planet and the X-Men were the only ones that could stop it. While many of the other X-Men failed in their attempts to stop the Hecatomb, Lady Mastermind’s illusions were real enough to trick the mental being and slow it down for a while. Regan’s heroic moment quickly faded as things started to go bad again and her immediate reaction was to flee. Unfortunately for her, there was nowhere to run to. It was Rogue who managed to destroy the Hecatomb by absorbing the billions of minds within it into herself. [X-Men (2nd series) #197-199]
When Rogue returned to her old home in Mississippi to recover from her ordeal, Regan and the rest of the team followed her. When the X-Men were called to help, Lady Mastermind seemed just to hang out in the background. 
In truth, the X-Men should have been watching her more closely, as Lady Mastermind was about to reveal her true colors in the most brutal way possible. Unbeknownst to them, both Regan and Mystique had been recruited by Mister Sinister and were playing along until the right moment. With a house full of X-Men, Lady Mastermind dropped an illusion she had been holding and revealed the Marauders were there as well. The heroes were outnumbered, outsmarted and outmatched, and they quickly fell to the might of the deadly team. Sinister had been taking out every mutant with knowledge of the future and Rogue was on his list because she had read Destiny’s prophetic diaries. With the X-Men defeated and Rogue captured, Lady Mastermind and the Marauders returned to Sinister to wait for the next stage in their plan. [X-Men (2nd series) #200-201]
The reason for Mister Sinister’s actions became apparent when the first new mutant baby was born after M-Day. Sinister had sent some Marauders to claim the child but discovered someone had gotten there first. He knew the X-Men would come calling sooner or later and his assumption proved correct when his Antarctic base was raided. Regan stood by the Marauders and took on her former team, personally helping to take Wolverine out the fight. 
The X-Men left but the base was destroyed and so Regan accompanied Sinister to Muir Island, where he prepared for his endgame. After Sinister eventually got his hands on the child, the Marauders prepared for the inevitable attack from the X-Men. When the Blackbird jet was spotted, Regan cast the Muir Island complex in an illusion that hid any sign of the Marauders. Unfortunately for her, Wolverine was becoming well versed in how to spot an illusion and he saw through Regan’s, stabbing her through the torso. Bleeding out and at death’s door, Regan was no use in the following fight that saw the defeat of Sinister and the splintering of the X-Men. [Messiah Complex crossover]